Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells

Differences in gene-wide DNA methylation of the Alzheimer’s disease (AD)-associated genes BIN1, HLA-DRB5, SORL1, SLC24A4, and ABCA7 are reported to be associated with AD in post-mortem brain samples. We investigated whether the same associations could be found in leukocytes collected pre-mortem. Usi...

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Detalles Bibliográficos
Autores principales: Karlsson, Ida K, Ploner, Alexander, Wang, Yunzhang, Gatz, Margaret, Pedersen, Nancy L, Hägg, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980709/
https://www.ncbi.nlm.nih.gov/pubmed/36573011
http://dx.doi.org/10.1080/15592294.2022.2158285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980709/
https://www.ncbi.nlm.nih.gov/pubmed/36573011
http://dx.doi.org/10.1080/15592294.2022.2158285

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