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Identification of Sjögren’s syndrome patient subgroups by clustering of labial salivary gland DNA methylation profiles

Heterogeneity in Sjögren’s syndrome (SS), increasingly called Sjögren’s disease, suggests the presence of disease subtypes, which poses a major challenge for the diagnosis, management, and treatment of this autoimmune disorder. Previous work distinguished patient subgroups based on clinical symptoms...

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Detalles Bibliográficos
Autores principales: Chi, Calvin, Solomon, Olivia, Shiboski, Caroline, Taylor, Kimberly E., Quach, Hong, Quach, Diana, Barcellos, Lisa F., Criswell, Lindsey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980741/
https://www.ncbi.nlm.nih.gov/pubmed/36862625
http://dx.doi.org/10.1371/journal.pone.0281891