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Expanded characterization of in vitro polarized M0, M1, and M2 human monocyte-derived macrophages: Bioenergetic and secreted mediator profiles

Respiratory macrophage subpopulations exhibit unique phenotypes depending on their location within the respiratory tract, posing a challenge to in vitro macrophage model systems. Soluble mediator secretion, surface marker expression, gene signatures, and phagocytosis are among the characteristics th...

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Detalles Bibliográficos
Autores principales: Hickman, Elise, Smyth, Timothy, Cobos-Uribe, Catalina, Immormino, Robert, Rebuli, Meghan E., Moran, Timothy, Alexis, Neil E., Jaspers, Ilona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980743/
https://www.ncbi.nlm.nih.gov/pubmed/36862675
http://dx.doi.org/10.1371/journal.pone.0279037