An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets

Failures in mitophagy, a process by which damaged mitochondria are cleared, results in neurodegeneration, while enhancing mitophagy promotes the survival of dopaminergic neurons. Using an artificial intelligence platform, we employed a natural language processing approach to evaluate the semantic si...

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Detalles Bibliográficos
Autores principales: Moskal, Natalia, Visanji, Naomi P., Gorbenko, Olena, Narasimhan, Vijay, Tyrrell, Hannah, Nash, Jess, Lewis, Peter N., McQuibban, G. Angus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980794/
https://www.ncbi.nlm.nih.gov/pubmed/36862640
http://dx.doi.org/10.1371/journal.pbio.3001977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980794/
https://www.ncbi.nlm.nih.gov/pubmed/36862640
http://dx.doi.org/10.1371/journal.pbio.3001977

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