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An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets
Failures in mitophagy, a process by which damaged mitochondria are cleared, results in neurodegeneration, while enhancing mitophagy promotes the survival of dopaminergic neurons. Using an artificial intelligence platform, we employed a natural language processing approach to evaluate the semantic si...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980794/ https://www.ncbi.nlm.nih.gov/pubmed/36862640 http://dx.doi.org/10.1371/journal.pbio.3001977 |