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Acss2/HIF-2 signaling facilitates colon cancer growth and metastasis

The microenvironment of solid tumors is characterized by oxygen and glucose deprivation. Acss2/HIF-2 signaling coordinates essential genetic regulators including acetate-dependent acetyl CoA synthetase 2 (Acss2), Creb binding protein (Cbp), Sirtuin 1 (Sirt1), and Hypoxia Inducible Factor 2α (HIF-2α)...

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Detalles Bibliográficos
Autores principales: Garcia, Joseph A., Chen, Rui, Xu, Min, Comerford, Sarah A., Hammer, Robert E., Melton, Shelby D., Feagins, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980813/
https://www.ncbi.nlm.nih.gov/pubmed/36862715
http://dx.doi.org/10.1371/journal.pone.0282223