Protective Effects of Crocin Against Methotrexate-Induced Hepatotoxicity in Adult Male Albino Rats: Histological, Immunohistochemical, and Biochemical Study

Background: Among the many known adverse effects of methotrexate (MTX), hepatotoxicity stands out as a major drawback that limits its therapeutic applicability. There is growing evidence that crocin has antioxidant, anti-hyperglycemic, cardioprotective, and anti-inflammatory effects. This study'...

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Detalles Bibliográficos
Autores principales: AbdelKader, Ghada, Abdelaziz, Eman Z, Hassan, Ranya, Greish, Sahar M, Abogresha, Noha M, Sultan, Basma O, Yousef, Einas M, Morsi, Shereen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981239/
https://www.ncbi.nlm.nih.gov/pubmed/36874671
http://dx.doi.org/10.7759/cureus.34468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981239/
https://www.ncbi.nlm.nih.gov/pubmed/36874671
http://dx.doi.org/10.7759/cureus.34468

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