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Restoration of aquaporin-4 polarization in the spinal glymphatic system by metformin in rats with painful diabetic neuropathy

Painful diabetic neuropathy (PDN) is a common complication in patients with diabetes, and its underlying mechanism remains unclear. Aquaporin-4 (AQP4) plays a crucial role in removing metabolic waste in the glymphatic system. In this study, we aimed to explore the relationship between the spinal gly...

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Detalles Bibliográficos
Autores principales: Xu, Chiliang, Wang, Feixiang, Su, Can, Guo, Xiao, Li, Jiang, Lin, Jingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981323/
https://www.ncbi.nlm.nih.gov/pubmed/36719843
http://dx.doi.org/10.1097/WNR.0000000000001880