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Metabolic heterogeneity and cross-feeding within isogenic yeast populations captured by DILAC

Genetically identical cells are known to differ in many physiological parameters such as growth rate and drug tolerance. Metabolic specialization is believed to be a cause of such phenotypic heterogeneity, but detection of metabolically divergent subpopulations remains technically challenging. We de...

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Detalles Bibliográficos
Autores principales: Kamrad, Stephan, Correia-Melo, Clara, Szyrwiel, Lukasz, Aulakh, Simran Kaur, Bähler, Jürg, Demichev, Vadim, Mülleder, Michael, Ralser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981460/
https://www.ncbi.nlm.nih.gov/pubmed/36797484
http://dx.doi.org/10.1038/s41564-022-01304-8