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Metabolic heterogeneity and cross-feeding within isogenic yeast populations captured by DILAC
Genetically identical cells are known to differ in many physiological parameters such as growth rate and drug tolerance. Metabolic specialization is believed to be a cause of such phenotypic heterogeneity, but detection of metabolically divergent subpopulations remains technically challenging. We de...
Autores principales: | Kamrad, Stephan, Correia-Melo, Clara, Szyrwiel, Lukasz, Aulakh, Simran Kaur, Bähler, Jürg, Demichev, Vadim, Mülleder, Michael, Ralser, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981460/ https://www.ncbi.nlm.nih.gov/pubmed/36797484 http://dx.doi.org/10.1038/s41564-022-01304-8 |
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