Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut

The molecular bases of how host genetic variation impacts the gut microbiome remain largely unknown. Here we used a genetically diverse mouse population and applied systems genetics strategies to identify interactions between host and microbe phenotypes including microbial functions, using faecal me...

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Detalles Bibliográficos
Autores principales: Zhang, Qijun, Linke, Vanessa, Overmyer, Katherine A., Traeger, Lindsay L., Kasahara, Kazuyuki, Miller, Ian J., Manson, Daniel E., Polaske, Thomas J., Kerby, Robert L., Kemis, Julia H., Trujillo, Edna A., Reddy, Thiru R., Russell, Jason D., Schueler, Kathryn L., Stapleton, Donald S., Rabaglia, Mary E., Seldin, Marcus, Gatti, Daniel M., Keele, Gregory R., Pham, Duy T., Gerdt, Joseph P., Vivas, Eugenio I., Lusis, Aldons J., Keller, Mark P., Churchill, Gary A., Blackwell, Helen E., Broman, Karl W., Attie, Alan D., Coon, Joshua J., Rey, Federico E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981464/
https://www.ncbi.nlm.nih.gov/pubmed/36759753
http://dx.doi.org/10.1038/s41564-023-01326-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981464/
https://www.ncbi.nlm.nih.gov/pubmed/36759753
http://dx.doi.org/10.1038/s41564-023-01326-w

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