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DNA G-quadruplex-stabilizing metal complexes as anticancer drugs
Guanine quadruplexes (G4s) are important targets for cancer treatments as their stabilization has been associated with a reduction of telomere ends or a lower oncogene expression. Although less abundant than purely organic ligands, metal complexes have shown remarkable abilities to stabilize G4s, an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981530/ https://www.ncbi.nlm.nih.gov/pubmed/36456886 http://dx.doi.org/10.1007/s00775-022-01973-0 |