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DNA G-quadruplex-stabilizing metal complexes as anticancer drugs

Guanine quadruplexes (G4s) are important targets for cancer treatments as their stabilization has been associated with a reduction of telomere ends or a lower oncogene expression. Although less abundant than purely organic ligands, metal complexes have shown remarkable abilities to stabilize G4s, an...

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Detalles Bibliográficos
Autores principales: Zegers, Jaccoline, Peters, Maartje, Albada, Bauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981530/
https://www.ncbi.nlm.nih.gov/pubmed/36456886
http://dx.doi.org/10.1007/s00775-022-01973-0