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A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes

In prophase of the first meiotic division, chromatin forms a compact spherical cluster called the karyosome within the enlarged oocyte nucleus in Drosophila melanogaster. Similar clustering of chromatin has been widely observed in oocytes in many species including humans. It was previously shown tha...

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Detalles Bibliográficos
Autores principales: Nieken, Karen Jule, O’Brien, Kathryn, McDonnell, Alexander, Zhaunova, Liudmila, Ohkura, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981535/
https://www.ncbi.nlm.nih.gov/pubmed/36648541
http://dx.doi.org/10.1007/s00412-023-00784-9