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TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression

Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Virtually all women with DCIS are treated, despite evidence suggesting up to half would remain with stable, non-threatening, disease. Overtreatment thus presents a pressing issue in DCIS management. To understand...

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Detalles Bibliográficos
Autores principales: Gibson, Shayin V., Tomas Bort, Elena, Rodríguez-Fernández, Lucía, Allen, Michael D., Gomm, Jennifer J., Goulding, Iain, auf dem Keller, Ulrich, Agnoletto, Andrea, Brisken, Cathrin, Peck, Barrie, Cameron, Angus J., Marshall, John F., Jones, J. Louise, Carter, Edward P., Grose, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981685/
https://www.ncbi.nlm.nih.gov/pubmed/36864079
http://dx.doi.org/10.1038/s41523-023-00513-6