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MAPK4 silencing in gastric cancer drives liver metastasis by positive feedback between cancer cells and macrophages

Liver metastasis is a major cause of death in gastric cancer patients, but the underlying mechanisms are poorly understood. Through a combination of in vivo screening and transcriptome profiling followed by quantitative RT-PCR and tissue array analyses, we found that mitogen-activated protein kinase...

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Detalles Bibliográficos
Autores principales: Li, Shuang, Guo, Dongyang, Sun, Qiang, Zhang, Lu, Cui, Yun, Liu, Min, Ma, Xixi, Liu, Yiman, Cui, Wenyu, Sun, Leimin, Teng, Lisong, Wang, Liangjing, Lin, Aifu, Liu, Wei, Zhuo, Wei, Zhou, Tianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981715/
https://www.ncbi.nlm.nih.gov/pubmed/36797541
http://dx.doi.org/10.1038/s12276-023-00946-w