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Structural features discriminating hybrid histidine kinase Rec domains from response regulator homologs

In two-component systems, the information gathered by histidine kinases (HKs) are relayed to cognate response regulators (RRs). Thereby, the phosphoryl group of the auto-phosphorylated HK is transferred to the receiver (Rec) domain of the RR to allosterically activate its effector domain. In contras...

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Detalles Bibliográficos
Autores principales: Brüderlin, Mitchell, Böhm, Raphael, Fadel, Firas, Hiller, Sebastian, Schirmer, Tilman, Dubey, Badri N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981736/
https://www.ncbi.nlm.nih.gov/pubmed/36864019
http://dx.doi.org/10.1038/s41467-023-36597-8