Superenhancers as master gene regulators and novel therapeutic targets in brain tumors

Transcriptional deregulation, a cancer cell hallmark, is driven by epigenetic abnormalities in the majority of brain tumors, including adult glioblastoma and pediatric brain tumors. Epigenetic abnormalities can activate epigenetic regulatory elements to regulate the expression of oncogenes. Superenh...

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Detalles Bibliográficos
Autores principales: Zhuang, Hai-Hui, Qu, Qiang, Teng, Xin-Qi, Dai, Ying-Huan, Qu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981748/
https://www.ncbi.nlm.nih.gov/pubmed/36720920
http://dx.doi.org/10.1038/s12276-023-00934-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981748/
https://www.ncbi.nlm.nih.gov/pubmed/36720920
http://dx.doi.org/10.1038/s12276-023-00934-0

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