Destin2: Integrative and cross-modality analysis of single-cell chromatin accessibility data

We propose Destin2, a novel statistical and computational method for cross-modality dimension reduction, clustering, and trajectory reconstruction for single-cell ATAC-seq data. The framework integrates cellular-level epigenomic profiles from peak accessibility, motif deviation score, and pseudo-gen...

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Detalles Bibliográficos
Autores principales: Guan, Peter Y., Lee, Jin Seok, Wang, Lihao, Lin, Kevin Z., Mei, Wenwen, Chen, Li, Jiang, Yuchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981783/
https://www.ncbi.nlm.nih.gov/pubmed/36873935
http://dx.doi.org/10.3389/fgene.2023.1089936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981783/
https://www.ncbi.nlm.nih.gov/pubmed/36873935
http://dx.doi.org/10.3389/fgene.2023.1089936

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