Cargando…

The protein kinase R modifies gut physiology to limit colitis

Here we investigate the function of the innate immune molecule protein kinase R (PKR) in intestinal inflammation. To model a colitogenic role of PKR, we determine the physiological response to dextran sulfate sodium (DSS) of wild-type and two transgenic mice strains mutated to express either a kinas...

Descripción completa

Detalles Bibliográficos
Autores principales: Yim, Howard Chi Ho, Chakrabarti, Arindam, Kessler, Sean, Morimoto, Hiroyuki, Wang, Die, Sooraj, Dhanya, Ahmed, Afsar U., de la Motte, Carol, Silverman, Robert H., Williams, Bryan RG., Sadler, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981792/
https://www.ncbi.nlm.nih.gov/pubmed/36875104
http://dx.doi.org/10.3389/fimmu.2023.1106737