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The protein kinase R modifies gut physiology to limit colitis
Here we investigate the function of the innate immune molecule protein kinase R (PKR) in intestinal inflammation. To model a colitogenic role of PKR, we determine the physiological response to dextran sulfate sodium (DSS) of wild-type and two transgenic mice strains mutated to express either a kinas...
Autores principales: | Yim, Howard Chi Ho, Chakrabarti, Arindam, Kessler, Sean, Morimoto, Hiroyuki, Wang, Die, Sooraj, Dhanya, Ahmed, Afsar U., de la Motte, Carol, Silverman, Robert H., Williams, Bryan RG., Sadler, Anthony J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981792/ https://www.ncbi.nlm.nih.gov/pubmed/36875104 http://dx.doi.org/10.3389/fimmu.2023.1106737 |
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