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An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone

Tumor progression is intimately associated with the vasculature, as tumor proliferation induces angiogenesis and tumor cells metastasize to distant organs via blood vessels. However, whether tumor invasion is associated with blood vessels remains unknown. As glioblastoma (GBM) is featured by aggress...

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Detalles Bibliográficos
Autores principales: Lee, Eunhyeong, Lee, Eun-Ah, Kong, Eunji, Chon, Haemin, Llaiqui-Condori, Melissa, Park, Cheon Ho, Park, Beom Yong, Kang, Nu Ri, Yoo, Jin-San, Lee, Hyun-Soo, Kim, Hyung-Seok, Park, Sung-Hong, Choi, Seung-Won, Vestweber, Dietmar, Lee, Jeong Ho, Kim, Pilhan, Lee, Weon Sup, Kim, Injune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981882/
https://www.ncbi.nlm.nih.gov/pubmed/36828931
http://dx.doi.org/10.1038/s12276-023-00939-9