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Short-term tamoxifen administration improves hepatic steatosis and glucose intolerance through JNK/MAPK in mice

Nonalcoholic fatty liver disease (NAFLD) which is a leading cause of chronic liver diseases lacks effective treatment. Tamoxifen has been proven to be the first-line chemotherapy for several solid tumors in clinics, however, its therapeutic role in NAFLD has never been elucidated before. In vitro ex...

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Detalles Bibliográficos
Autores principales: Fang, Zhiqiang, Xu, Hao, Duan, Juanli, Ruan, Bai, Liu, Jingjing, Song, Ping, Ding, Jian, Xu, Chen, Li, Zhiwen, Dou, Kefeng, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981902/
https://www.ncbi.nlm.nih.gov/pubmed/36864030
http://dx.doi.org/10.1038/s41392-022-01299-y