Targeting fat mass and obesity-associated protein mitigates human colorectal cancer growth in vitro and in a murine model

INTRODUCTION: Colorectal cancer (CRC) remains a significant cause of cancer related mortality. Fat mass and obesity-associated protein (FTO) is a m6A mRNA demethylase that plays an oncogenic role in various malignancies. In this study we evaluated the role of FTO in CRC tumorigenesis. METHODS: Cell...

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Detalles Bibliográficos
Autores principales: Phan, Thuy, Nguyen, Vu H., Su, Rui, Li, Yangchan, Qing, Ying, Qin, Hanjun, Cho, Hyejin, Jiang, Lei, Wu, Xiwei, Chen, Jianjun, Fakih, Marwan, Diamond, Don J., Goel, Ajay, Melstrom, Laleh G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981948/
https://www.ncbi.nlm.nih.gov/pubmed/36874096
http://dx.doi.org/10.3389/fonc.2023.1087644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981948/
https://www.ncbi.nlm.nih.gov/pubmed/36874096
http://dx.doi.org/10.3389/fonc.2023.1087644

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