Alleviation of cognitive deficits in a rat model of glutamate-induced excitotoxicity, using an N-type voltage-gated calcium channel ligand, extracted from Agelena labyrinthica crude venom

Excitotoxicity is a common pathological process in Alzheimer’s disease (AD) which is caused by the over-activity of N-Methyl-D-Aspartate receptors (NMDARs). The release of neurotransmitters depends on the activity of voltage-gated calcium channels (VGCCs). Hyper-stimulation of NMDARs can enhance the...

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Detalles Bibliográficos
Autores principales: Keimasi, Mohammad, Salehifard, Kowsar, Keimasi, Mohammadjavad, Amirsadri, Mohammadreza, Esfahani, Noushin Mirshah Jafar, Moradmand, Majid, Esmaeili, Fariba, Mofid, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981952/
https://www.ncbi.nlm.nih.gov/pubmed/36873105
http://dx.doi.org/10.3389/fnmol.2023.1123343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981952/
https://www.ncbi.nlm.nih.gov/pubmed/36873105
http://dx.doi.org/10.3389/fnmol.2023.1123343

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