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Deep Crypt Secretory Cell Differentiation in the Colonic Epithelium Is Regulated by Sprouty2 and Interleukin 13

BACKGROUND & AIMS: Deep crypt secretory (DCS) cells are a critical component of the colonic stem cell niche. However, the regulatory mechanisms controlling DCS cell numbers and function are not well understood. Sprouty2 is an inflammation-responsive regulator of intracellular signaling that infl...

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Detalles Bibliográficos
Autores principales: Schumacher, Michael A., Liu, Cambrian Y., Katada, Kay, Thai, Megan H., Hsieh, Jonathan J., Hansten, Britany J., Waddell, Amanda, Rosen, Michael J., Frey, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982040/
https://www.ncbi.nlm.nih.gov/pubmed/36414210
http://dx.doi.org/10.1016/j.jcmgh.2022.11.004