Self-Assembled Matrigel-Free iPSC-Derived Liver Organoids Demonstrate Wide-Ranging Highly Differentiated Liver Functions

Human induced pluripotent stem cell (iPSC)-derived liver organoids serve as models of organogenesis, disease, drug screening, and regenerative medicine. Prevailing methods for generating organoids rely on Matrigel, whose batch-to-batch variability and xenogeneic source pose challenges to mechanistic...

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Detalles Bibliográficos
Autores principales: Weng, Yun, Han, Simon, Sekyi, Maria T, Su, Tao, Mattis, Aras N, Chang, Tammy T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982071/
https://www.ncbi.nlm.nih.gov/pubmed/36573434
http://dx.doi.org/10.1093/stmcls/sxac090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982071/
https://www.ncbi.nlm.nih.gov/pubmed/36573434
http://dx.doi.org/10.1093/stmcls/sxac090

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