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PHLDA1 modulates microglial response and NLRP3 inflammasome signaling following experimental subarachnoid hemorrhage

Balancing microglia M1/M2 polarization is an effective therapeutic strategy for neuroinflammation after subarachnoid hemorrhage (SAH). Pleckstrin homology-like domain family A member 1 (PHLDA1) has been demonstrated to play a crucial role in immune response. However, the function roles of PHLDA1 in...

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Detalles Bibliográficos
Autores principales: Lai, Jinqing, Chen, Genwang, Wu, Zhe, Yu, Shaoyang, Huang, Rongfu, Zeng, Yile, Lin, Weibin, Fan, Chunmei, Chen, Xiangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982097/
https://www.ncbi.nlm.nih.gov/pubmed/36875102
http://dx.doi.org/10.3389/fimmu.2023.1105973