Deficiency of the RNA-binding protein ELAVL1/HuR leads to the failure of endogenous and exogenous neuroprotection of retinal ganglion cells

INTRODUCTION: ELAVL1/HuR is a keystone regulator of gene expression at the posttranscriptional level, including stress response and homeostasis maintenance. The aim of this study was to evaluate the impact of hur silencing on the age-related degeneration of retinal ganglion cells (RGC), which potent...

Descripción completa

Detalles Bibliográficos
Autores principales: Pacwa, Anna, Machowicz, Joanna, Akhtar, Saeed, Rodak, Piotr, Liu, Xiaonan, Pietrucha-Dutczak, Marita, Lewin-Kowalik, Joanna, Amadio, Marialaura, Smedowski, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982123/
https://www.ncbi.nlm.nih.gov/pubmed/36874215
http://dx.doi.org/10.3389/fncel.2023.1131356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982123/
https://www.ncbi.nlm.nih.gov/pubmed/36874215
http://dx.doi.org/10.3389/fncel.2023.1131356

Ejemplares similares