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Simvastatin Upregulates Lipoxin A4 and Accelerates Neuroinflammation Resolution After Intracerebral Hemorrhage

BACKGROUND: Previous studies have demonstrated that statins can relieve inflammatory brain injury after intracerebral hemorrhage (ICH), but the mechanisms remain poorly characterized. This study aims to test whether simvastatin exerts an anti-inflammatory effect by regulating the pro-resolving media...

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Detalles Bibliográficos
Autores principales: Zhang, Jianbo, Hao, Na, Li, Wei, Chen, Qianwei, Chen, Zhi, Feng, Hua, Wu, Yao, Shi, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982195/
https://www.ncbi.nlm.nih.gov/pubmed/36100985
http://dx.doi.org/10.2174/1567202619666220913124627