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Successful naltrexone-bupropion treatment after several treatment failures in a patient with severe monogenic obesity
We describe the therapeutic journey of a 33-year-old patient with early-onset obesity (BMI 56.7 kg/m(2)) and hyperphagia due to a likely pathogenic heterozygous melanocortin-4 receptor (MC4R) gene variant. She was unsuccessfully treated with several intensive lifestyle interventions, gastric bypass...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982263/ https://www.ncbi.nlm.nih.gov/pubmed/36876127 http://dx.doi.org/10.1016/j.isci.2023.106199 |