m(6)A demethylase ALKBH5 attenuates doxorubicin-induced cardiotoxicity via posttranscriptional stabilization of Rasal3

The clinical application of anthracyclines such as doxorubicin (DOX) is limited due to their cardiotoxicity. N6-methyladenosine (m(6)A) plays an essential role in numerous biological processes. However, the roles of m(6)A and m(6)A demethylase ALKBH5 in DOX-induced cardiotoxicity (DIC) remain unclea...

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Detalles Bibliográficos
Autores principales: Gao, Ri-Feng, Yang, Kun, Qu, Ya-Nan, Wei, Xiang, Shi, Jia-Ran, Lv, Chun-Yu, Zhao, Yong-Chao, Sun, Xiao-Lei, Xu, Ying-Jia, Yang, Yi-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982307/
https://www.ncbi.nlm.nih.gov/pubmed/36876119
http://dx.doi.org/10.1016/j.isci.2023.106215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982307/
https://www.ncbi.nlm.nih.gov/pubmed/36876119
http://dx.doi.org/10.1016/j.isci.2023.106215

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