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Intravitreal air tamponade after AAV2 subretinal injection modifies retinal EGFP distribution

The subretinal injection protocol for the only approved retinal gene therapy (voretigene neparvovec-rzyl) includes air tamponade at the end of the procedure, but its effects on the subretinal bleb have not been described. In the present study, we evaluated the distribution of enhanced green fluoresc...

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Detalles Bibliográficos
Autores principales: Ducloyer, Jean-Baptiste, Pichard, Virginie, Mevel, Mathieu, Galy, Anne, Lefevre, Gaelle M., Brument, Nicole, Alvarez-Dorta, Dimitri, Deniaud, David, Mendes-Madeira, Alexandra, Libeau, Lyse, Le Guiner, Caroline, Cronin, Therese, Adjali, Oumeya, Weber, Michel, Le Meur, Guylène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982454/
https://www.ncbi.nlm.nih.gov/pubmed/36874242
http://dx.doi.org/10.1016/j.omtm.2023.02.006