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Nano‐Brake Halts Mitochondrial Dysfunction Cascade to Alleviate Neuropathology and Rescue Alzheimer's Cognitive Deficits

Mitochondrial dysfunction has been recognized as the key pathogenesis of most neurodegenerative diseases including Alzheimer's disease (AD). The dysregulation of mitochondrial calcium ion (Ca(2+)) homeostasis and the mitochondrial permeability transition pore (mPTP), is a critical upstream sign...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Song, Qingxiang, Yu, Renhe, Wang, Antian, Jiang, Gan, Huang, Yukun, Chen, Jun, Xu, Jianrong, Wang, Dayuan, Chen, Hongzhuan, Gao, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982524/
https://www.ncbi.nlm.nih.gov/pubmed/36703613
http://dx.doi.org/10.1002/advs.202204596