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Nano‐Brake Halts Mitochondrial Dysfunction Cascade to Alleviate Neuropathology and Rescue Alzheimer's Cognitive Deficits
Mitochondrial dysfunction has been recognized as the key pathogenesis of most neurodegenerative diseases including Alzheimer's disease (AD). The dysregulation of mitochondrial calcium ion (Ca(2+)) homeostasis and the mitochondrial permeability transition pore (mPTP), is a critical upstream sign...
Autores principales: | Zhang, Qian, Song, Qingxiang, Yu, Renhe, Wang, Antian, Jiang, Gan, Huang, Yukun, Chen, Jun, Xu, Jianrong, Wang, Dayuan, Chen, Hongzhuan, Gao, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982524/ https://www.ncbi.nlm.nih.gov/pubmed/36703613 http://dx.doi.org/10.1002/advs.202204596 |
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