Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils

Development of abdominal aortic aneurysms (AAA) enhances lesion group‐2 innate lymphoid cell (ILC2) accumulation and blood IL5. ILC2 deficiency in Rora(fl/fl)Il7r(Cre/+) mice or induced ILC2 depletion in Icos(fl‐DTR‐fl/+)Cd4(Cre/+) mice expedites AAA growth, increases lesion inflammation, but leads...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanyuan, Liu, Tianxiao, Deng, Zhiyong, Fang, Wenqian, Zhang, Xian, Zhang, Shuya, Wang, Minjie, Luo, Songyuan, Meng, Zhaojie, Liu, Jing, Sukhova, Galina K., Li, Dazhu, McKenzie, Andrew N. J., Libby, Peter, Shi, Guo‐Ping, Guo, Junli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982556/
https://www.ncbi.nlm.nih.gov/pubmed/36592421
http://dx.doi.org/10.1002/advs.202206958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982556/
https://www.ncbi.nlm.nih.gov/pubmed/36592421
http://dx.doi.org/10.1002/advs.202206958

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