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Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils
Development of abdominal aortic aneurysms (AAA) enhances lesion group‐2 innate lymphoid cell (ILC2) accumulation and blood IL5. ILC2 deficiency in Rora(fl/fl)Il7r(Cre/+) mice or induced ILC2 depletion in Icos(fl‐DTR‐fl/+)Cd4(Cre/+) mice expedites AAA growth, increases lesion inflammation, but leads...
Autores principales: | Zhang, Yuanyuan, Liu, Tianxiao, Deng, Zhiyong, Fang, Wenqian, Zhang, Xian, Zhang, Shuya, Wang, Minjie, Luo, Songyuan, Meng, Zhaojie, Liu, Jing, Sukhova, Galina K., Li, Dazhu, McKenzie, Andrew N. J., Libby, Peter, Shi, Guo‐Ping, Guo, Junli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982556/ https://www.ncbi.nlm.nih.gov/pubmed/36592421 http://dx.doi.org/10.1002/advs.202206958 |
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