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Single‐Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma

Lymph node metastasis, the leading cause of mortality in esophageal squamous carcinoma (ESCC) with a highly complex tumor microenvironment, remains underexplored. Here, the transcriptomes of 85 263 single cells are analyzed from four ESCC patients with lymph node metastases. Strikingly, it is observ...

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Detalles Bibliográficos
Autores principales: Jia, Yongxu, Zhang, Baifeng, Zhang, Chunyang, Kwong, Dora Lai‐Wan, Chang, Zhiwei, Li, Shanshan, Wang, Zehua, Han, Huiqiong, Li, Jing, Zhong, Yali, Sui, Xin, Fu, Li, Guan, Xinyuan, Qin, Yanru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982558/
https://www.ncbi.nlm.nih.gov/pubmed/36709495
http://dx.doi.org/10.1002/advs.202204565