LncRNA LIMp27 Regulates the DNA Damage Response through p27 in p53‐Defective Cancer Cells

P53 inactivation occurs in about 50% of human cancers, where p53‐driven p21 activity is devoid and p27 becomes essential for the establishment of the G1/S checkpoint upon DNA damage. Here, this work shows that the E2F1‐responsive lncRNA LIMp27 selectively represses p27 expression and contributes to...

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Detalles Bibliográficos
Autores principales: La, Ting, Chen, Song, Zhao, Xiao Hong, Zhou, Shuai, Xu, Ran, Teng, Liu, Zhang, Yuan Yuan, Ye, Kaihong, Xu, Liang, Guo, Tao, Jamaluddin, Muhammad Fairuz, Feng, Yu Chen, Tang, Hai Jie, Wang, Yanliang, Xu, Qin, Gu, Yue, Cao, Huixia, Liu, Tao, Thorne, Rick F., Shao, Feng‐Min, Zhang, Xu Dong, Jin, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982580/
https://www.ncbi.nlm.nih.gov/pubmed/36638271
http://dx.doi.org/10.1002/advs.202204599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982580/
https://www.ncbi.nlm.nih.gov/pubmed/36638271
http://dx.doi.org/10.1002/advs.202204599

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