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AdipoRon accelerates bone repair of calvarial defect in diet-induced obesity mice

OBJECTIVES: To investigate the role of AdipoRon in bone wound healing of calvaria critical-sized defects (CSD) in diet-induced obesity (DIO) mice. MATERIALS AND METHODS: After establishing the calvaria CSD in normal-chow (NC), DIO and Adiponectin knockout (APNKO) mice, AdipoRon or vehicle was orally...

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Detalles Bibliográficos
Autores principales: Wu, Xingwen, Zhu, Danting, Shi, Le, Tu, Qisheng, Yu, Youcheng, Chen, Jake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982622/
https://www.ncbi.nlm.nih.gov/pubmed/36873496
http://dx.doi.org/10.1016/j.heliyon.2023.e13975