NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis

Metabolic reprogramming and metabolic plasticity allow cancer cells to fine-tune their metabolism and adapt to the ever-changing environments of the metastatic cascade, for which lipid metabolism and oxidative stress are of particular importance. NADPH is a central co-factor for both lipid and redox...

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Detalles Bibliográficos
Autores principales: Ilter, Didem, Drapela, Stanislav, Schild, Tanya, Ward, Nathan P., Adhikari, Emma, Low, Vivien, Asara, John, Oskarsson, Thordur, Lau, Eric K., DeNicola, Gina M., McReynolds, Melanie R., Gomes, Ana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982641/
https://www.ncbi.nlm.nih.gov/pubmed/36841051
http://dx.doi.org/10.1016/j.redox.2023.102627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982641/
https://www.ncbi.nlm.nih.gov/pubmed/36841051
http://dx.doi.org/10.1016/j.redox.2023.102627

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