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NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis
Metabolic reprogramming and metabolic plasticity allow cancer cells to fine-tune their metabolism and adapt to the ever-changing environments of the metastatic cascade, for which lipid metabolism and oxidative stress are of particular importance. NADPH is a central co-factor for both lipid and redox...
Autores principales: | Ilter, Didem, Drapela, Stanislav, Schild, Tanya, Ward, Nathan P., Adhikari, Emma, Low, Vivien, Asara, John, Oskarsson, Thordur, Lau, Eric K., DeNicola, Gina M., McReynolds, Melanie R., Gomes, Ana P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982641/ https://www.ncbi.nlm.nih.gov/pubmed/36841051 http://dx.doi.org/10.1016/j.redox.2023.102627 |
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