Low and differential polygenic score generalizability among African populations due largely to genetic diversity

African populations are vastly underrepresented in genetic studies but have the most genetic variation and face wide-ranging environmental exposures globally. Because systematic evaluations of genetic prediction had not yet been conducted in ancestries that span African diversity, we calculated poly...

Descripción completa

Detalles Bibliográficos
Autores principales: Majara, Lerato, Kalungi, Allan, Koen, Nastassja, Tsuo, Kristin, Wang, Ying, Gupta, Rahul, Nkambule, Lethukuthula L., Zar, Heather, Stein, Dan J., Kinyanda, Eugene, Atkinson, Elizabeth G., Martin, Alicia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982687/
https://www.ncbi.nlm.nih.gov/pubmed/36873096
http://dx.doi.org/10.1016/j.xhgg.2023.100184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9982687/
https://www.ncbi.nlm.nih.gov/pubmed/36873096
http://dx.doi.org/10.1016/j.xhgg.2023.100184

Ejemplares similares