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Exosomes from tubular epithelial cells undergoing epithelial‐to‐mesenchymal transition promote renal fibrosis by M1 macrophage activation

Kidney fibrosis is the common final pathway of chronic kidney disease (CKD), and it is distinguished by inflammation, mesenchymal transition with myofibroblast formation, and epithelial‐to‐mesenchymal transition (EMT). Macrophages are protuberant inflammatory cells in the kidney, and their roles are...

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Detalles Bibliográficos
Autores principales: Lu, Yuqing, Zhang, Rui, Gu, Xiameng, Wang, Xuerong, Xi, Peipei, Chen, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983075/
https://www.ncbi.nlm.nih.gov/pubmed/36876297
http://dx.doi.org/10.1096/fba.2022-00080