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Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming

BACKGROUND: Chemotherapy (CT) is central to the treatment of triple negative breast cancer (TNBC), but drug toxicity and resistance place strong restrictions on treatment regimes. Fasting sensitizes cancer cells to a range of chemotherapeutic agents and also ameliorates CT-associated adverse effects...

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Detalles Bibliográficos
Autores principales: Pateras, Ioannis S., Williams, Chloe, Gianniou, Despoina D., Margetis, Aggelos T., Avgeris, Margaritis, Rousakis, Pantelis, Legaki, Aigli-Ioanna, Mirtschink, Peter, Zhang, Wei, Panoutsopoulou, Konstantina, Delis, Anastasios D., Pagakis, Stamatis N., Tang, Wei, Ambs, Stefan, Warpman Berglund, Ulrika, Helleday, Thomas, Varvarigou, Anastasia, Chatzigeorgiou, Antonios, Nordström, Anders, Tsitsilonis, Ourania E., Trougakos, Ioannis P., Gilthorpe, Jonathan D., Frisan, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983166/
https://www.ncbi.nlm.nih.gov/pubmed/36869333
http://dx.doi.org/10.1186/s12967-023-03935-9