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Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming
BACKGROUND: Chemotherapy (CT) is central to the treatment of triple negative breast cancer (TNBC), but drug toxicity and resistance place strong restrictions on treatment regimes. Fasting sensitizes cancer cells to a range of chemotherapeutic agents and also ameliorates CT-associated adverse effects...
Autores principales: | Pateras, Ioannis S., Williams, Chloe, Gianniou, Despoina D., Margetis, Aggelos T., Avgeris, Margaritis, Rousakis, Pantelis, Legaki, Aigli-Ioanna, Mirtschink, Peter, Zhang, Wei, Panoutsopoulou, Konstantina, Delis, Anastasios D., Pagakis, Stamatis N., Tang, Wei, Ambs, Stefan, Warpman Berglund, Ulrika, Helleday, Thomas, Varvarigou, Anastasia, Chatzigeorgiou, Antonios, Nordström, Anders, Tsitsilonis, Ourania E., Trougakos, Ioannis P., Gilthorpe, Jonathan D., Frisan, Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983166/ https://www.ncbi.nlm.nih.gov/pubmed/36869333 http://dx.doi.org/10.1186/s12967-023-03935-9 |
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