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Activation of the Hedgehog signaling pathway leads to fibrosis in aortic valves

BACKGROUND: Fibrosis is a pathological wound healing process characterized by excessive extracellular matrix deposition, which interferes with normal organ function and contributes to ~ 45% of human mortality. Fibrosis develops in response to chronic injury in nearly all organs, but the a cascade of...

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Detalles Bibliográficos
Autores principales: Gu, Dongsheng, Soepriatna, Arvin H., Zhang, Wenjun, Li, Jun, Zhao, Jenny, Zhang, Xiaoli, Shu, Xianhong, Wang, Yongshi, Landis, Benjamin J., Goergen, Craig J., Xie, Jingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983197/
https://www.ncbi.nlm.nih.gov/pubmed/36864465
http://dx.doi.org/10.1186/s13578-023-00980-1