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PSnpBind-ML: predicting the effect of binding site mutations on protein-ligand binding affinity
Protein mutations, especially those which occur in the binding site, play an important role in inter-individual drug response and may alter binding affinity and thus impact the drug’s efficacy and side effects. Unfortunately, large-scale experimental screening of ligand-binding against protein varia...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983232/ https://www.ncbi.nlm.nih.gov/pubmed/36864534 http://dx.doi.org/10.1186/s13321-023-00701-3 |