Selenite as a dual apoptotic and ferroptotic agent synergizes with EGFR and KRAS inhibitors with epigenetic interference

BACKGROUND: Selenium, an essential trace element, has previously been investigated as a pro-apoptotic and DNA demethylation agent. It sensitizes the response to chemotherapy in patients who were refractory to cytotoxic agents. Meanwhile, ferroptosis is a novel approach to cancer treatment by trigger...

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Detalles Bibliográficos
Autores principales: Chan, Lok Seng, Liu, Johnson, Li, Molly S. C., Li, Lili, Tao, Qian, Mok, Tony S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983273/
https://www.ncbi.nlm.nih.gov/pubmed/36864513
http://dx.doi.org/10.1186/s13148-023-01454-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983273/
https://www.ncbi.nlm.nih.gov/pubmed/36864513
http://dx.doi.org/10.1186/s13148-023-01454-4

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