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Hsa‐miR‐409‐3p regulates endothelial progenitor senescence via PP2A‐P38 and is a potential ageing marker in humans

We explored the roles of hsa‐microRNA (miR)‐409‐3p in senescence and signalling mechanism of human endothelial progenitor cells (EPCs). Hsa‐miR‐409‐3p was found upregulated in senescent EPCs. Overexpression of miRNA mimics in young EPCs inhibited angiogenesis. In senescent EPCs, compared to young EP...

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Detalles Bibliográficos
Autores principales: Lee, Yi‐Nan, Wu, Yih‐Jer, Lee, Hsin‐I, Wang, Hsueh‐Hsiao, Hung, Chung‐Lieh, Chang, Chiung‐Yin, Chou, Yen‐Hung, Tien, Ting‐Yi, Lee, Chun‐Wei, Lin, Chao‐Feng, Su, Cheng‐Huang, Yeh, Hung‐I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983318/
https://www.ncbi.nlm.nih.gov/pubmed/36756741
http://dx.doi.org/10.1111/jcmm.17691