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Astragaloside IV improves pulmonary arterial hypertension by increasing the expression of CCN1 and activating the ERK1/2 pathway

The aim of the present study was to investigate the underlying mechanism of AS‐IV and CCN1 in PAH and to evaluate whether the protective effect of AS‐IV against PAH is associated with CCN1 and its related signalling pathway. In vivo, male SD rats were intraperitoneally injected with monocrotaline (M...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Tang, Bai‐Lin, Lu, Mei‐Li, Wang, Hong‐Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983322/
https://www.ncbi.nlm.nih.gov/pubmed/36762748
http://dx.doi.org/10.1111/jcmm.17681